iPTMnet Report for Q16602 (CALCRL)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16602 / CALRL_HUMAN
Protein Name Calcitonin gene-related peptide type 1 receptor precursor
Gene Name Name: CALCRL
Synonyms:CGRPR;
Organism Homo sapiens (Human)

PRO ID PR:Q16602
DAG View
PRO Name calcitonin gene-related peptide type 1 receptor (human)
Definition A calcitonin gene-related peptide type 1 receptor that is encoded in the genome of human.
Short Label hCALCRL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16602 (CALCRL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N66 N-Glycosylation GlyGen 11389975, 24190977
N110 N-Glycosylation GlyGen 24190977
N118 N-Glycosylation GlyGen 11389975, 24190977
N123 N-Glycosylation GlyGen 11389975, 24190977
S285 Phosphorylation PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus
Y460 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N123 D123 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
S285 C285 Biomuta DOID:1324 / lung cancer [ tcga ]
K403 E403 Biomuta DOID:1909 / melanoma [ tcga ] DOID:1324 / lung cancer [ tcga ]
S409 R409 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S445 N445 Biomuta DOID:1324 / lung cancer [ cosmic ]
S445 R445 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ]