iPTMnet Report for Q16602 (CALCRL)
Protein Information
UniProt AC / UniProt ID | Q16602 / CALRL_HUMAN |
Protein Name | Calcitonin gene-related peptide type 1 receptor precursor |
Gene Name | Name: CALCRL Synonyms:CGRPR; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q16602 |
PRO Name | calcitonin gene-related peptide type 1 receptor (human) |
Definition | A calcitonin gene-related peptide type 1 receptor that is encoded in the genome of human. |
Short Label | hCALCRL |
Category | organism-gene |
Q16602 (CALCRL) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N66 | N-Glycosylation | score3 | GlyGen | 11389975, 24190977 | ||
N110 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N118 | N-Glycosylation | score3 | GlyGen | 11389975, 24190977 | ||
N123 | N-Glycosylation | score3 | GlyGen | 11389975, 24190977 | ||
S285 | Phosphorylation | score1 | PhosphoSitePlus | |||
K403 | Ubiquitination | score1 | PhosphoSitePlus | |||
S409 | Phosphorylation | score1 | PhosphoSitePlus | |||
S445 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y460 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N123 | D123 | Biomuta | DOID:9256 / colorectal cancer [ icgc, tcga ] | |
S285 | C285 | Biomuta | DOID:1324 / lung cancer [ tcga ] | |
K403 | E403 | Biomuta | DOID:1909 / melanoma [ tcga ] DOID:1324 / lung cancer [ tcga ] | |
S409 | R409 | Biomuta | DOID:5041 / esophageal cancer [ icgc ] | |
S445 | N445 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S445 | R445 | Biomuta | DOID:3571 / liver cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ] |