iPTMnet Report for Q16587 (ZNF74)
Protein Information
UniProt AC / UniProt ID | Q16587 / ZNF74_HUMAN |
Protein Name | Zinc finger protein 74 |
Gene Name | Name: ZNF74 Synonyms:ZNF520; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q16587 |
PRO Name | zinc finger protein 74 (human) |
Definition | A zinc finger protein 74 that is encoded in the genome of human. |
Short Label | hZNF74 |
Category | organism-gene |
Q16587 (ZNF74) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K23 | Ubiquitination | score1 | PhosphoSitePlus | |||
S62 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 32357974 | ||
S123 | Phosphorylation | score1 | IEDB | 35494241 | ||
K231 | Ubiquitination | score1 | PhosphoSitePlus | |||
T327 | Phosphorylation | score1 | PhosphoSitePlus | |||
S342 | Phosphorylation | score1 | PhosphoSitePlus | |||
T355 | Phosphorylation | score1 | PhosphoSitePlus | |||
K358 | Ubiquitination | score1 | PhosphoSitePlus | |||
T383 | Phosphorylation | score1 | PhosphoSitePlus | |||
T437 | Phosphorylation | score1 | PhosphoSitePlus | |||
T439 | Phosphorylation | score1 | PhosphoSitePlus | |||
S467 | Phosphorylation | score1 | PhosphoSitePlus | |||
T523 | Phosphorylation | score1 | PhosphoSitePlus | |||
K554 | Acetylation | score1 | PhosphoSitePlus | |||
K557 | Acetylation | score1 | PhosphoSitePlus | |||
S637 | Phosphorylation | score1 | PhosphoSitePlus | |||
S640 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R70 | Methylation | score1 | PhosphoSitePlus | |||
R116 | Methylation | score1 | PhosphoSitePlus | |||
R125 | Methylation | score1 | PhosphoSitePlus | |||
R164 | Methylation | score1 | PhosphoSitePlus | |||
R175 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R70 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R116 | L116 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
R164 | Q164 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
R175 | H175 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T327 | M327 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
T437 | M437 | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] | |
S467 | T467 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
S637 | F637 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |