Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16587 / ZNF74_HUMAN
Protein Name Zinc finger protein 74
Gene Name Name: ZNF74
Synonyms:ZNF520;
Organism Homo sapiens (Human)

PRO ID PR:Q16587
DAG View
PRO Name zinc finger protein 74 (human)
Definition A zinc finger protein 74 that is encoded in the genome of human.
Short Label hZNF74
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16587 (ZNF74) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K23 Ubiquitination PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
T327 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
T355 Phosphorylation PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
T383 Phosphorylation PhosphoSitePlus
T437 Phosphorylation PhosphoSitePlus
T439 Phosphorylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
T523 Phosphorylation PhosphoSitePlus
K554 Acetylation PhosphoSitePlus
K557 Acetylation PhosphoSitePlus
S637 Phosphorylation PhosphoSitePlus
S640 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
R70 Methylation PhosphoSitePlus
R116 Methylation PhosphoSitePlus
R125 Methylation PhosphoSitePlus
R164 Methylation PhosphoSitePlus
R175 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T327 M327 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
T437 M437 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
T439 M439 Biomuta DOID:5041 / esophageal cancer [ icgc ]
K554 T554 Biomuta DOID:363 / uterine cancer [ tcga ]
K557 N557 Biomuta DOID:3571 / liver cancer [ icgc ]
S637 F637 Biomuta DOID:1909 / melanoma [ tcga ]