iPTMnet Report for Q16587 (ZNF74)
Protein Information
| UniProt AC / UniProt ID | Q16587 / ZNF74_HUMAN |
| Protein Name | Zinc finger protein 74 |
| Gene Name | Name: ZNF74 Synonyms:ZNF520; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q16587 |
| PRO Name | zinc finger protein 74 (human) |
| Definition | A zinc finger protein 74 that is encoded in the genome of human. |
| Short Label | hZNF74 |
| Category | organism-gene |
Q16587 (ZNF74) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K23 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S62 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 32357974 | ||
| S123 | Phosphorylation | score1 | IEDB | 35494241 | ||
| K231 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T327 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S342 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T355 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K358 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T383 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T437 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T439 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S467 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T523 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K554 | Acetylation | score1 | PhosphoSitePlus | |||
| K557 | Acetylation | score1 | PhosphoSitePlus | |||
| S637 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S640 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| R70 | Methylation | score1 | PhosphoSitePlus | |||
| R116 | Methylation | score1 | PhosphoSitePlus | |||
| R125 | Methylation | score1 | PhosphoSitePlus | |||
| R164 | Methylation | score1 | PhosphoSitePlus | |||
| R175 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R70 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R116 | L116 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| R164 | Q164 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| R175 | H175 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T327 | M327 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
| T437 | M437 | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] | |
| S467 | T467 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
| S637 | F637 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View