Protein Information

Cytoscape View

UniProt AC / UniProt ID Q16581 / C3AR_HUMAN
Protein Name C3a anaphylatoxin chemotactic receptor
Gene Name Name: C3AR1
Organism Homo sapiens (Human)

PRO ID PR:Q16581
DAG View
PRO Name C3a anaphylatoxin chemotactic receptor (human)
Definition A C3a anaphylatoxin chemotactic receptor that is encoded in the genome of human.
Short Label hC3AR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q16581 (C3AR1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S266 O-Glycosylation UniProt 23234360
S266 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
S459 Phosphorylation PhosphoSitePlus
T463 Phosphorylation PhosphoSitePlus   RLIMS-P 23077507
S465 Phosphorylation PhosphoSitePlus   RLIMS-P 23077507
T466 Phosphorylation PhosphoSitePlus   RLIMS-P 23077507
S470 Phosphorylation PhosphoSitePlus   RLIMS-P 23077507
S475 Phosphorylation RLIMS-P 23077507
S479 Phosphorylation PhosphoSitePlus   RLIMS-P 23077507
T480 Phosphorylation RLIMS-P 23077507
T481 Phosphorylation RLIMS-P 23077507

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S266 P266 Biomuta DOID:363 / uterine cancer [ tcga ]
S349 P349 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S349 F349 Biomuta DOID:1324 / lung cancer [ tcga ]
S349 C349 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S470 * Biomuta DOID:5041 / esophageal cancer [ icgc ]
S479 N479 Biomuta DOID:363 / uterine cancer [ tcga ]