iPTMnet Report for Q16576 (RBBP7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16576 / RBBP7_HUMAN
Protein Name Histone-binding protein RBBP7
Gene Name Name: RBBP7
Synonyms:RBAP46;
Organism Homo sapiens (Human)

PRO ID PR:Q16576
DAG View
PRO Name histone-binding protein RBBP7 (human)
Definition A histone-binding protein RBBP7 that is encoded in the genome of human.
Short Label hRBBP7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16576 (RBBP7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 21406692, 22814378, ...20068231
S3 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
K4 Acetylation PhosphoSitePlus   UniProt 19608861
K4 Sumoylation PhosphoSitePlus
K4 Ubiquitination PhosphoSitePlus
T10 Phosphorylation PhosphoSitePlus   UniProt 23186163
E13 Phosphorylation UniProt 20068231
R14 Methylation PhosphoSitePlus
Y20 Phosphorylation PhosphoSitePlus
K21 Acetylation PhosphoSitePlus
K21 Sumoylation PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
Y60 Phosphorylation PhosphoSitePlus
S95 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S99 Phosphorylation PhosphoSitePlus
K101 Acetylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
K113 Sumoylation PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
K119 Acetylation PhosphoSitePlus
K119 Sumoylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
R130 Methylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
T143 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
S146 Phosphorylation PhosphoSitePlus
T154 Phosphorylation PhosphoSitePlus
K155 Sumoylation PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K159 Acetylation PhosphoSitePlus
K159 Methylation PhosphoSitePlus
K159 Sumoylation PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
C202 Methylation IEDB 31844290
K214 Ubiquitination PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
R257 Methylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
T296 Phosphorylation PhosphoSitePlus
R303 Methylation PhosphoSitePlus
K306 Sumoylation PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
R340 Methylation PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
S354 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163, ...20068231
S413 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
T416 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation HPRD 19007248
S95 Phosphorylation HPRD 18669648, 20068231
S354 Phosphorylation HPRD 18691976, 18669648, 20068231, ...18452278
S413 Phosphorylation HPRD 17287340, 19007248, 20068231
T416 Phosphorylation HPRD 17287340, 19007248
Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y20 C20 Biomuta DOID:3571 / liver cancer [ cosmic ]
S109 Y109 Biomuta DOID:1319 / brain cancer [ cosmic ]
K119 Q119 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R130 C130 Biomuta DOID:363 / uterine cancer [ icgc ]
T154 K154 Biomuta DOID:3571 / liver cancer [ cosmic ]
R303 H303 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R303 C303 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K308 R308 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S314 Y314 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K316 T316 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R340 H340 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc, tcga ]
S347 C347 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S354 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S413 A413 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T416 M416 Biomuta DOID:9256 / colorectal cancer [ cosmic ]