Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16352 / AINX_HUMAN
Protein Name Alpha-internexin
Gene Name Name: INA
Synonyms:NEF5;
Organism Homo sapiens (Human)

PRO ID PR:Q16352
DAG View
PRO Name alpha-internexin (human)
Definition An alpha-internexin that is encoded in the genome of human.
Short Label hINA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16352 (INA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus
R24 Methylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
R39 Methylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
R104 Methylation PhosphoSitePlus
Y272 Phosphorylation PhosphoSitePlus
Y287 Phosphorylation PhosphoSitePlus
K290 Acetylation PhosphoSitePlus   UniProt 19608861
K290 Ubiquitination PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
R377 Methylation PhosphoSitePlus
Y379 Phosphorylation PhosphoSitePlus
Y396 Phosphorylation PhosphoSitePlus
K398 Acetylation PhosphoSitePlus
T442 Phosphorylation PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus
T463 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
K483 Acetylation PhosphoSitePlus
S496 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17525332
K498 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K95 N95 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
K290 T290 Biomuta DOID:10534 / stomach cancer [ icgc, tcga ] DOID:1909 / melanoma [ tcga ]
R377 Q377 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
R377 W377 Biomuta DOID:1324 / lung cancer [ icgc, tcga ]
S464 F464 Biomuta DOID:1909 / melanoma [ icgc ]