iPTMnet Report for Q16270 (IGFBP7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16270 / IBP7_HUMAN
Protein Name Insulin-like growth factor-binding protein 7 precursor
Gene Name Name: IGFBP7
Synonyms:MAC25,PSF;
Organism Homo sapiens (Human)

PRO ID PR:Q16270
DAG View
PRO Name insulin-like growth factor-binding protein 7 (human)
Definition An insulin-like growth factor-binding protein 7 that is encoded in the genome of human.
Short Label hIGFBP7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16270 (IGFBP7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T31 O-Glycosylation GlyGen 30459171
S39 O-Glycosylation GlyGen 30459171
K114 Ubiquitination PhosphoSitePlus
Y117 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
N171 N-Glycosylation GlyGen   UniProt 8939990
T188 O-Glycosylation GlyGen 30459171
Y201 Phosphorylation PhosphoSitePlus
T206 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T220 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T230 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S236 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S239 Phosphorylation PhosphoSitePlus   UniProt 26091039
S253 Phosphorylation PhosphoSitePlus
T264 O-Glycosylation GlyGen   PhosphoSitePlus 23584533


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K146 T146 Biomuta DOID:4159 / skin cancer [ cosmic ]