iPTMnet Report for Q16222 (UAP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16222 / UAP1_HUMAN
Protein Name UDP-N-acetylhexosamine pyrophosphorylase
Gene Name Name: UAP1
Synonyms:SPAG2;
Organism Homo sapiens (Human)

PRO ID PR:Q16222
DAG View
PRO Name UDP-N-acetylhexosamine pyrophosphorylase (human)
Definition A UDP-N-acetylhexosamine pyrophosphorylase that is encoded in the genome of human.
Short Label hUAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16222 (UAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Ubiquitination PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
Y125 Phosphorylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
Y153 Phosphorylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
T170 Phosphorylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K180 Acetylation PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
K182 Acetylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
C293 S-Nitrosylation dbSNO 2212679, 22126794, 26338901
Y299 Phosphorylation PhosphoSitePlus
Y304 Phosphorylation PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
Y360 Phosphorylation PhosphoSitePlus
T363 Phosphorylation PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
K407 Ubiquitination PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
C431 Methylation IEDB 31844290
K472 Acetylation PhosphoSitePlus
K472 Ubiquitination PhosphoSitePlus
C481 Methylation IEDB 31844290
K519 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K7 E7 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K63 N63 Biomuta DOID:363 / uterine cancer [ icgc ]
K213 N213 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K391 T391 Biomuta DOID:363 / uterine cancer [ icgc ]
K391 Q391 Biomuta DOID:1324 / lung cancer [ cosmic ]
K407 N407 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]