iPTMnet Report for Q16206 (ENOX2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16206 / ENOX2_HUMAN
Protein Name Ecto-NOX disulfide-thiol exchanger 2
Gene Name Name: ENOX2
Synonyms:COVA1;
Organism Homo sapiens (Human)

PRO ID PR:Q16206
DAG View
PRO Name ecto-NOX disulfide-thiol exchanger 2 (human)
Definition An ecto-NOX disulfide-thiol exchanger 2 that is encoded in the genome of human.
Short Label hENOX2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16206 (ENOX2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S240 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
T352 Phosphorylation PhosphoSitePlus
S389 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
Y428 Phosphorylation PhosphoSitePlus
K436 Ubiquitination PhosphoSitePlus
K489 Acetylation PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 22659163, 31635402
S504 Phosphorylation Q05655 (PRKCD) PhosphoSitePlus   Signor 22659163
Site PTM Type PTM Enzyme Score Source PMID
S389 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
S360 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S343 F343 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S420 I420 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y428 * Biomuta DOID:1324 / lung cancer [ cosmic ]