iPTMnet Report for Q16186 (ADRM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16186 / ADRM1_HUMAN
Protein Name Proteasomal ubiquitin receptor ADRM1
Gene Name Name: ADRM1
Synonyms:GP110;
Organism Homo sapiens (Human)

PRO ID PR:Q16186
DAG View
PRO Name proteasomal ubiquitin receptor ADRM1 (human)
Definition A proteasomal ubiquitin receptor ADRM1 that is encoded in the genome of human.
Short Label hADRM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16186 (ADRM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Acetylation UniProt 19413330, 22814378, 22223895
T2 Phosphorylation HPRD   PhosphoSitePlus 19651622, 20068231
T3 Phosphorylation HPRD 19651622
S4 Phosphorylation HPRD 20068231
S10 Phosphorylation HPRD 20068231
S15 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 23186163
S19 Phosphorylation PhosphoSitePlus
K21 Acetylation PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
Y22 Phosphorylation PhosphoSitePlus
R27 Methylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
K34 Methylation PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
T37 Phosphorylation PhosphoSitePlus
T39 Phosphorylation HPRD   PhosphoSitePlus 20068231
K42 Methylation PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K83 Acetylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
C88 Methylation IEDB 31844290
K97 Ubiquitination PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
Y127 Phosphorylation PhosphoSitePlus   UniProt 24275569
S140 Phosphorylation PhosphoSitePlus   UniProt 24275569
S142 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
S211 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 22661428, 29237092, 34725712, 31373491, 34105348, 32574038, 35132862, 29485866, 28657654, 34846842, 33214551, 30379171, 30059200, 29351928, 34019948, 20563614, 34229054
S211 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243, 19664995
S213 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 22661428, 29237092, 34725712, 31373491, 34105348, 32574038, 35132862, 29485866, 28657654, 34846842, 33214551, 30379171, 30059200, 29351928, 34019948, 20563614, 34229054
S213 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 18669648
T217 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 22661428, 29237092, 34725712, 31373491, 34105348, 32574038, 35132862, 29485866, 28657654, 34846842, 33214551, 30379171, 30059200, 29351928, 34019948, 20563614, 34229054
T217 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 16964243, ...19664995, 18669648
S219 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 22661428, 29237092, 34725712, 31373491, 34105348, 32574038, 35132862, 29485866, 28657654, 34846842, 33214551, 30379171, 30059200, 29351928, 34019948, 20563614, 34229054
S219 Phosphorylation PhosphoSitePlus
S220 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 22661428, 29237092, 34725712, 31373491, 34105348, 32574038, 35132862, 29485866, 28657654, 34846842, 33214551, 30379171, 30059200, 29351928, 34019948, 20563614, 34229054
S220 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 19664995
T221 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 22661428, 29237092, 34725712, 31373491, 34105348, 32574038, 35132862, 29485866, 28657654, 34846842, 33214551, 30379171, 30059200, 29351928, 34019948, 20563614, 34229054
T221 Phosphorylation PhosphoSitePlus
T222 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 22661428, 29237092, 34725712, 31373491, 34105348, 32574038, 35132862, 29485866, 28657654, 34846842, 33214551, 30379171, 30059200, 29351928, 34019948, 20563614, 34229054
T222 Phosphorylation HPRD   phospho.ELM 18669648
S223 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 22661428, 29237092, 34725712, 31373491, 34105348, 32574038, 35132862, 29485866, 28657654, 34846842, 33214551, 30379171, 30059200, 29351928, 34019948, 20563614, 34229054
S224 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 22661428, 29237092, 34725712, 31373491, 34105348, 32574038, 35132862, 29485866, 28657654, 34846842, 33214551, 30379171, 30059200, 29351928, 34019948, 20563614, 34229054
S224 Phosphorylation PhosphoSitePlus
T225 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 22661428, 29237092, 34725712, 31373491, 34105348, 32574038, 35132862, 29485866, 28657654, 34846842, 33214551, 30379171, 30059200, 29351928, 34019948, 20563614, 34229054
K371 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
S405 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 17081983, ...20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T2 A2 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K21 R21 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y22 F22 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R27 L27 Biomuta DOID:1324 / lung cancer [ cosmic ]
S32 P32 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T37 I37 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K83 T83 Biomuta DOID:3571 / liver cancer [ cosmic ]
S140 N140 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S219 L219 Biomuta DOID:4362 / cervical cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
T221 A221 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T225 P225 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K371 M371 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K379 E379 Biomuta DOID:3571 / liver cancer [ cosmic ]
K395 R395 Biomuta DOID:10534 / stomach cancer [ cosmic ]