iPTMnet Report for Q16134 (ETFDH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16134 / ETFD_HUMAN
Protein Name Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor
Gene Name Name: ETFDH
Organism Homo sapiens (Human)

PRO ID PR:Q16134
DAG View
PRO Name electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (human)
Definition An electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial that is encoded in the genome of human.
Short Label hETFDH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16134 (ETFDH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T31 Phosphorylation PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
K125 Acetylation PhosphoSitePlus
K132 Acetylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
Y172 Phosphorylation PhosphoSitePlus
T216 Phosphorylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
K357 Acetylation PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
Y361 Phosphorylation PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
T427 Phosphorylation PhosphoSitePlus
T433 Phosphorylation PhosphoSitePlus
Y435 Phosphorylation PhosphoSitePlus
S551 Phosphorylation PhosphoSitePlus   UniProt 24275569


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T31 I31 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K125 N125 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S373 F373 Biomuta DOID:3571 / liver cancer [ cosmic ]
T433 I433 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S551 L551 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]