iPTMnet Report for Q15942 (ZYX)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15942 / ZYX_HUMAN
Protein Name Zyxin
Gene Name Name: ZYX
Organism Homo sapiens (Human)

PRO ID PR:Q15942
DAG View
PRO Name zyxin (human)
Definition A zyxin that is encoded in the genome of human.
Short Label hZYX
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15942 (ZYX) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
R5 Methylation PhosphoSitePlus
S7 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
S7 Phosphorylation PhosphoSitePlus
S11 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
S13 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
S13 Phosphorylation PhosphoSitePlus
S15 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
S15 Phosphorylation PhosphoSitePlus
Y20 Phosphorylation PhosphoSitePlus
K24 Acetylation PhosphoSitePlus
K25 Acetylation PhosphoSitePlus
K25 Methylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus   UniProt 24275569
S142 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17287340, 23233529, 33808029, ...24275569, 17572661
S142 Phosphorylation P31749 (AKT1) neXtProt   PhosphoSitePlus   Signor 17572661
S143 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
K165 Acetylation PhosphoSitePlus
K165 Methylation PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
S169 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 32938750, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447
S169 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S170 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
S170 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
Y172 Phosphorylation PhosphoSitePlus
T179 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
T179 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17287340, 20068231
S182 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
S183 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
K201 Methylation PhosphoSitePlus
S202 O-Glycosylation GlyGen 31373491
S202 Phosphorylation PhosphoSitePlus
S206 O-Glycosylation GlyGen 31373491
S206 Phosphorylation PhosphoSitePlus
S218 O-Glycosylation GlyGen 31373491
T220 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
S240 O-Glycosylation GlyGen 23301498, 35138101, 30459171, ...30620550, 31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
T242 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
S246 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
T250 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
T250 Phosphorylation PhosphoSitePlus
R253 Methylation PhosphoSitePlus
S258 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
S258 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S259 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
S259 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 16964243, 15302935, ...18669648, 24275569, 23186163, 20068231
K265 Acetylation PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
S267 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
S267 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18088087, 15302935, ...18669648, 24275569, 23186163
T270 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
K272 Acetylation PhosphoSitePlus
K272 Methylation PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
T274 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S278 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 35254053, 29237092, 34725712, 28657654, 32119511, 31637018, 35227760, 32574038, 35132862, 31373491, 27655845, 33214551, 30379171, 30059200, 29351928, 34019948, 28510447
S278 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K279 Acetylation PhosphoSitePlus   UniProt 19608861
K279 Methylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
S281 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 24275569, 18088087, 20068231
S288 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S290 O-Glycosylation GlyGen 31373491
S290 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 16964243
K295 Ubiquitination PhosphoSitePlus
S303 O-Glycosylation GlyGen 31373491
S303 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983, 18847512
S303 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
T306 O-Glycosylation GlyGen 31373491
T306 Phosphorylation PhosphoSitePlus 18847512
T306 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
S308 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18220336, ...18847512, 18669648, 20068231
S308 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
S313 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
T315 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y316 Phosphorylation PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
R343 Methylation PhosphoSitePlus
S344 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18088087, 17081983, ...15302935, 18669648, 17287340, 24275569, 23186163, 20068231, 16964243
T352 Phosphorylation PhosphoSitePlus
C409 Methylation IEDB 31844290
C467 Methylation IEDB 31844290
S505 Phosphorylation PhosphoSitePlus
K528 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S142 Phosphorylation HPRD 19651622, 20166139, 17287340, ...20068231, 18452278
S143 Phosphorylation HPRD 18491316, 17081983, 20058876, ...18452278, 19651622, 18707149, 20166139, 20068231, 17924679
S150 Phosphorylation HPRD 20068231
S169 Phosphorylation HPRD 18669648, 20068231
S170 Phosphorylation HPRD 18669648, 20068231
Y172 Phosphorylation HPRD 20068231
T179 Phosphorylation HPRD 17287340, 20068231
S258 Phosphorylation HPRD 19651622, 18669648, 19664995, ...20068231
S259 Phosphorylation HPRD 20058876, 16964243, 15302935, ...19664994, 19664995, 19651622, 18669648, 19415658, 20068231, 17924679
S267 Phosphorylation HPRD 19413330, 17322306, 18088087, ...19651622, 18669648, 19415658, 20068231
T270 Phosphorylation HPRD 19413330, 18767875, 18669648, ...19651622
T274 Phosphorylation HPRD 18669648, 20068231
S278 Phosphorylation HPRD 18669648, 20068231
S281 Phosphorylation HPRD 19413330, 18088087, 16964243, ...15302935, 20058876, 19664995, 19651622, 18669648, 19415658, 20068231
S288 Phosphorylation HPRD 19413330, 19651622, 18669648, ...20068231
S290 Phosphorylation HPRD 18669648, 16964243, 19415658
S303 Phosphorylation HPRD 18669648, 17081983, 20068231
T306 Phosphorylation HPRD 17081983, 20068231, 19664995
S308 Phosphorylation HPRD 17081983, 19664995, 19651622, ...18669648, 19415658, 20068231
S313 Phosphorylation HPRD 18669648, 20068231
T315 Phosphorylation HPRD 18669648, 20068231
S344 Phosphorylation HPRD 16964243, 17322306, 18578522, ...18088087, 18212344, 18767875, 19664994, 19664995, 19651622, 18669648, 20058876, 18707149, 20166139, 17287340, 20068231, 17924679
T352 Phosphorylation HPRD 17081983