iPTMnet Report for Q15878 (CACNA1E)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15878 / CAC1E_HUMAN
Protein Name Voltage-dependent R-type calcium channel subunit alpha-1E
Gene Name Name: CACNA1E
Synonyms:CACH6,CACNL1A6;
Organism Homo sapiens (Human)

PRO ID PR:Q15878
DAG View
PRO Name voltage-dependent R-type calcium channel subunit alpha-1E (human)
Definition A voltage-dependent R-type calcium channel subunit alpha-1E that is encoded in the genome of human.
Short Label hCACNA1E
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15878 (CACNA1E) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T635 Phosphorylation PhosphoSitePlus
S637 Phosphorylation PhosphoSitePlus
S815 Phosphorylation PhosphoSitePlus
S816 Phosphorylation PhosphoSitePlus
Y1217 Phosphorylation PhosphoSitePlus
C1281 Methylation IEDB 31844290
K1454 Ubiquitination PhosphoSitePlus
C1504 Methylation IEDB 31844290
T1567 Phosphorylation PhosphoSitePlus
S1568 Phosphorylation PhosphoSitePlus
T1683 Phosphorylation PhosphoSitePlus
S1686 Phosphorylation PhosphoSitePlus
S1861 Phosphorylation PhosphoSitePlus
T1864 Phosphorylation PhosphoSitePlus
S1975 Phosphorylation PhosphoSitePlus
S2053 Phosphorylation PhosphoSitePlus
Y2054 Phosphorylation PhosphoSitePlus
S2056 Phosphorylation PhosphoSitePlus
S2057 Phosphorylation PhosphoSitePlus
K2087 Acetylation PhosphoSitePlus
K2090 Acetylation PhosphoSitePlus
S2142 Phosphorylation PhosphoSitePlus
S2145 Phosphorylation PhosphoSitePlus
S2263 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S637 L637 Biomuta DOID:4159 / skin cancer [ cosmic ]
C1504 Y1504 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S1686 T1686 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1861 F1861 Biomuta [ cosmic ]
S2056 F2056 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2057 F2057 Biomuta DOID:4159 / skin cancer [ cosmic ]
K2087 T2087 Biomuta DOID:263 / kidney cancer [ cosmic ]
K2090 T2090 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2145 F2145 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2145 C2145 Biomuta DOID:3571 / liver cancer [ cosmic ]
S2145 Y2145 Biomuta DOID:1324 / lung cancer [ cosmic ]