iPTMnet Report for Q15853 (USF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15853 / USF2_HUMAN
Protein Name Upstream stimulatory factor 2
Gene Name Name: USF2
Synonyms:BHLHB12;
Organism Homo sapiens (Human)

PRO ID PR:Q15853
DAG View
PRO Name upstream stimulatory factor 2 (human)
Definition An upstream stimulatory factor 2 that is encoded in the genome of human.
Short Label hUSF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15853 (USF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T85 O-Glycosylation GlyGen 34019948, 29351928
T95 O-Glycosylation GlyGen 34019948, 29351928
S103 O-Glycosylation GlyGen 34019948, 29351928
S155 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   RLIMS-P 25238393, 31013770
Y221 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus   RLIMS-P 31013770
K224 Ubiquitination PhosphoSitePlus
T228 Phosphorylation PhosphoSitePlus
T230 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   RLIMS-P 25238393
K250 Ubiquitination PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
T272 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
C284 Methylation IEDB 31844290
T293 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
K302 Ubiquitination PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T293 Phosphorylation HPRD 17081983
Site PTM Type PTM Enzyme Score Source PMID
S88 Phosphorylation PhosphoSitePlus
T226 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S88 N88 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S155 N155 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K250 N250 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K271 N271 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T272 M272 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]