iPTMnet Report for Q15836 (VAMP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15836 / VAMP3_HUMAN
Protein Name Vesicle-associated membrane protein 3
Gene Name Name: VAMP3
Synonyms:SYB3;
Organism Homo sapiens (Human)

PRO ID PR:Q15836
DAG View
PRO Name vesicle-associated membrane protein 3 (human)
Definition A vesicle-associated membrane protein 3 that is encoded in the genome of human.
Short Label hVAMP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15836 (VAMP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378, 25944712
S2 Phosphorylation PhosphoSitePlus
T3 Phosphorylation HPRD   PhosphoSitePlus 20068231
T9 Phosphorylation PhosphoSitePlus
S11 Phosphorylation HPRD   PhosphoSitePlus 18578522
T18 Phosphorylation PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
S44 Phosphorylation HPRD   PhosphoSitePlus 20068231
R49 Methylation PhosphoSitePlus
S58 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18578522, 17525332
T62 Phosphorylation PhosphoSitePlus
S63 Phosphorylation HPRD   PhosphoSitePlus 18578522, 20068231
K66 Ubiquitination PhosphoSitePlus   UniProt 23353890
K68 Ubiquitination PhosphoSitePlus   UniProt 23353890
K77 Ubiquitination UniProt 23353890


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 F2 Biomuta DOID:363 / uterine cancer [ icgc ]
R49 S49 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R49 H49 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
R49 C49 Biomuta DOID:363 / uterine cancer [ icgc, tcga ]
S58 F58 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]