iPTMnet Report for Q15776 (ZKSCAN8)
Protein Information
| UniProt AC / UniProt ID | Q15776 / ZKSC8_HUMAN |
| Protein Name | Zinc finger protein with KRAB and SCAN domains 8 |
| Gene Name | Name: ZKSCAN8 Synonyms:ZNF192; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q15776 |
| PRO Name | zinc finger protein with KRAB and SCAN domains 8 (human) |
| Definition | A zinc finger protein with KRAB and SCAN domains 8 that is encoded in the genome of human. |
| Short Label | hZKSCAN8 |
| Category | organism-gene |
Q15776 (ZKSCAN8) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S12 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| T17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K26 | Sumoylation | score1 | PhosphoSitePlus | |||
| S37 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y59 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T62 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S141 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S177 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S183 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
| S189 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S191 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
| S193 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T195 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
| S197 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K199 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K241 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K272 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K288 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T317 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T345 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S388 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T401 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K413 | Sumoylation | score1 | PhosphoSitePlus | |||
| S429 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S446 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S447 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T457 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T470 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S483 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T485 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K502 | Sumoylation | score1 | PhosphoSitePlus | |||
| K502 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T513 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K519 | Acetylation | score1 | PhosphoSitePlus | |||
| K521 | Acetylation | score1 | PhosphoSitePlus | |||
| T541 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S569 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K572 | Sumoylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S12 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 18452278 | ||
| S42 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S177 | Phosphorylation | score0 | HPRD | 19007248, 19691289 | ||
| S183 | Phosphorylation | score0 | HPRD | 17525332 | ||
| S191 | Phosphorylation | score0 | HPRD | 17525332 | ||
| T195 | Phosphorylation | score0 | HPRD | 17525332 | ||
| T317 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S12 | A12 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T17 | I17 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S42 | I42 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| S141 | L141 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S177 | F177 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S191 | F191 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T195 | A195 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S429 | N429 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S447 | L447 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K502 | N502 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| T513 | I513 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| T541 | I541 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
DAG View