Protein Information

Cytoscape View

UniProt AC / UniProt ID Q15768 / EFNB3_HUMAN
Protein Name Ephrin-B3 precursor
Gene Name Name: EFNB3
Organism Homo sapiens (Human)

PRO ID PR:Q15768
DAG View
PRO Name ephrin-B3 (human)
Definition An ephrin-B3 that is encoded in the genome of human.
Short Label hEFNB3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q15768 (EFNB3) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S268 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y311 Phosphorylation PhosphoSitePlus
Y318 Phosphorylation PRO   PhosphoSitePlus
Y323 Phosphorylation PRO   PhosphoSitePlus
S332 Phosphorylation RLIMS-P 26479588
Y337 Phosphorylation PRO   PhosphoSitePlus
Y338 Phosphorylation PhosphoSitePlus


PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047259 (hEFNB3/SigPep-/Phos:1) pY318,pY323,pY337 PRO

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q15768 (EFNB3) S332 P78352 (DLG4) inhibited_association eFIP 26479588

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S274 A274 Biomuta DOID:1324 / lung cancer [ tcga ]
S274 F274 Biomuta DOID:1909 / melanoma [ tcga ]
S332 G332 Biomuta DOID:363 / uterine cancer [ tcga ]
S332 N332 Biomuta DOID:1324 / lung cancer [ cosmic ]