iPTMnet Report for Q15762 (CD226)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15762 / CD226_HUMAN
Protein Name CD226 antigen precursor
Gene Name Name: CD226
Synonyms:DNAM1;
Organism Homo sapiens (Human)

PRO ID PR:Q15762
DAG View
PRO Name CD226 antigen (human)
Definition A CD226 molecule that is encoded in the genome of human.
Short Label hCD226
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15762 (CD226) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K167 Ubiquitination PhosphoSitePlus
N198 N-Glycosylation GlyGen 23090970, 24190977
Y249 Phosphorylation PhosphoSitePlus
T250 Phosphorylation PhosphoSitePlus
S290 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18088087
T293 Phosphorylation PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
Y322 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18088087, 14676297, 15684041, ...19690332, 10591186
Y322 Phosphorylation P06241 (FYN) PhosphoSitePlus 10591186
Y325 Phosphorylation PhosphoSitePlus
S329 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 15684041, 9712030
S329 Phosphorylation P17252 (PRKCA) PhosphoSitePlus 9712030


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y322 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y325 H325 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y325 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]