iPTMnet Report for Q15758 (SLC1A5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15758 / AAAT_HUMAN
Protein Name Neutral amino acid transporter B(0)
Gene Name Name: SLC1A5
Synonyms:ASCT2;
Organism Homo sapiens (Human)

PRO ID PR:Q15758
DAG View
PRO Name neutral amino acid transporter B(0) (human)
Definition A neutral amino acid transporter B(0) that is encoded in the genome of human.
Short Label hSLC1A5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15758 (SLC1A5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378
S9 Phosphorylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
Y38 Phosphorylation PhosphoSitePlus
N163 N-Glycosylation GlyGen 25862406
K178 Ubiquitination PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
N212 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 24190977, ...25862406, 19349973
K247 Ubiquitination PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
C467 Methylation IEDB 31844290
S493 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
T494 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K502 Ubiquitination PhosphoSitePlus
S503 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
K522 Sumoylation PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus
Y524 Phosphorylation PhosphoSitePlus
R525 Methylation PhosphoSitePlus
T532 Phosphorylation PhosphoSitePlus
S535 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18669648, ...19690332, 20068231
K537 Acetylation PhosphoSitePlus
K537 Ubiquitination PhosphoSitePlus
S539 Phosphorylation IEDB   PhosphoSitePlus   UniProt 34433824, 23186163
Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation HPRD 18578522
S198 Phosphorylation HPRD 20068231
S493 Phosphorylation HPRD 19651622, 18578522, 20068231
T494 Phosphorylation HPRD 18578522, 18669648, 20068231
S503 Phosphorylation HPRD 18669648
Y524 Phosphorylation HPRD 19901323, 18578522
T532 Phosphorylation HPRD 19413330, 18578522
S535 Phosphorylation HPRD 19651622, 18578522, 18669648, ...20068231, 17081983
S539 Phosphorylation HPRD 18578522


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S198 L198 Biomuta DOID:1324 / lung cancer [ cosmic ]
C467 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S493 I493 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K522 R522 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R525 Q525 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T532 M532 Biomuta DOID:1319 / brain cancer [ cosmic ]
S535 F535 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K537 E537 Biomuta DOID:363 / uterine cancer [ icgc ]