Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15738 / NSDHL_HUMAN
Protein Name Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating
Gene Name Name: NSDHL
Synonyms:H105E3;
Organism Homo sapiens (Human)

PRO ID PR:Q15738
DAG View
PRO Name sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (human)
Definition A sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating that is encoded in the genome of human.
Short Label hNSDHL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15738 (NSDHL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378, 22223895
T19 Phosphorylation PhosphoSitePlus
T22 Phosphorylation PhosphoSitePlus   UniProt 23186163
K24 Ubiquitination PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
Y164 Phosphorylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
T284 Phosphorylation PhosphoSitePlus
Y288 Phosphorylation PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
Y349 Phosphorylation PhosphoSitePlus
T354 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K31 N31 Biomuta DOID:1324 / lung cancer [ tcga ]
K167 N167 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K263 N263 Biomuta DOID:3571 / liver cancer [ icgc ]