Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15735 / PI5PA_HUMAN
Protein Name Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
Gene Name Name: INPP5J
Synonyms:PIB5PA,PIPP;
Organism Homo sapiens (Human)

PRO ID PR:Q15735
DAG View
PRO Name phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (human)
Definition A phosphatidylinositol 4,5-bisphosphate 5-phosphatase A that is encoded in the genome of human.
Short Label hINPP5J
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15735 (INPP5J) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R7 Methylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
T30 Phosphorylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
R56 Methylation PhosphoSitePlus
R65 Methylation PhosphoSitePlus
R76 Methylation PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
R83 Methylation PhosphoSitePlus
T91 Phosphorylation PhosphoSitePlus
S150 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
T154 O-Glycosylation GlyGen 28657654
S163 O-Glycosylation GlyGen 28657654
Y667 Phosphorylation PhosphoSitePlus
S694 Phosphorylation PhosphoSitePlus
S881 Phosphorylation PhosphoSitePlus
S886 Phosphorylation PhosphoSitePlus
S888 Phosphorylation PhosphoSitePlus
S902 Phosphorylation PhosphoSitePlus
S903 Phosphorylation PhosphoSitePlus   UniProt 23186163
S910 Phosphorylation PhosphoSitePlus
S912 Phosphorylation PhosphoSitePlus
S914 Phosphorylation PhosphoSitePlus
S917 Phosphorylation PhosphoSitePlus
S990 Phosphorylation PhosphoSitePlus   UniProt 23186163
S992 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S20 Y20 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S81 Y81 Biomuta DOID:363 / uterine cancer [ icgc ]
S694 N694 Biomuta DOID:363 / uterine cancer [ icgc ]
S881 C881 Biomuta DOID:4159 / skin cancer [ icgc ]
S886 G886 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S888 I888 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S914 * Biomuta DOID:4159 / skin cancer [ cosmic ]