iPTMnet Report for Q15723 (ELF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15723 / ELF2_HUMAN
Protein Name ETS-related transcription factor Elf-2
Gene Name Name: ELF2
Synonyms:NERF;
Organism Homo sapiens (Human)

PRO ID PR:Q15723
DAG View
PRO Name ETS-related transcription factor Elf-2 (human)
Definition An ETS-related transcription factor Elf-2 that is encoded in the genome of human.
Short Label hELF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15723 (ELF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S107 Phosphorylation PhosphoSitePlus   UniProt 23186163
C110 Methylation IEDB 31844290
S116 Phosphorylation PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
T158 Phosphorylation PhosphoSitePlus
T182 Phosphorylation PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S188 Phosphorylation PhosphoSitePlus
S191 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935, 19690332
K197 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
Y261 Phosphorylation PhosphoSitePlus
R269 Methylation PhosphoSitePlus
Y271 Phosphorylation PhosphoSitePlus
Y272 Phosphorylation PhosphoSitePlus
K279 Sumoylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
Y287 Phosphorylation PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
S349 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
T362 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
S363 Phosphorylation PhosphoSitePlus   UniProt 23186163
S369 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
S370 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
S372 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
S372 Phosphorylation PhosphoSitePlus   UniProt 18669648
T374 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
T374 Phosphorylation PhosphoSitePlus
T375 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...35254053, 32574038, 32938750, 34019948, 30059200, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092
T376 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
S378 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
S380 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
T382 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
T399 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
S400 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...35254053, 32574038, 32938750, 34019948, 30059200, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092
S406 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
S412 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
T421 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
S422 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
T423 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
S424 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
S424 Phosphorylation PhosphoSitePlus
T426 Phosphorylation PhosphoSitePlus
T427 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
T429 Phosphorylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus   UniProt 20068231
K451 Ubiquitination PhosphoSitePlus
T489 Phosphorylation PhosphoSitePlus
R494 Methylation PhosphoSitePlus   UniProt 24129315
T497 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
T497 Phosphorylation PhosphoSitePlus
S500 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...35254053, 32574038, 32938750, 34019948, 30059200, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092
S500 Phosphorylation PhosphoSitePlus
T505 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
T505 Phosphorylation PhosphoSitePlus
R509 Methylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
T521 Phosphorylation PhosphoSitePlus   UniProt 23186163
K531 Ubiquitination PhosphoSitePlus
K536 Sumoylation PhosphoSitePlus
K549 Sumoylation PhosphoSitePlus
K549 Ubiquitination PhosphoSitePlus
K557 Ubiquitination PhosphoSitePlus
T564 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
T566 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
S572 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...35254053, 32574038, 32938750, 34019948, 30059200, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092
S575 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
T582 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32574038, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550, 29237092, 30059200
T582 Phosphorylation PhosphoSitePlus
K584 Sumoylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S107 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
T170 Phosphorylation HPRD 19413330, 19651622, 20068231
S173 Phosphorylation HPRD 19413330, 19651622, 20068231
S176 Phosphorylation HPRD 19651622
S179 Phosphorylation HPRD 19413330, 20068231
S351 Phosphorylation HPRD 18669648
S360 Phosphorylation HPRD 18669648
T362 Phosphorylation HPRD 18669648
S410 Phosphorylation HPRD 20068231
S412 Phosphorylation HPRD 18669648, 20068231
T414 Phosphorylation HPRD 19413330
T415 Phosphorylation HPRD 18669648
T417 Phosphorylation HPRD 19413330
S418 Phosphorylation HPRD 19413330, 18669648, 20068231
T509 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
T122 Phosphorylation HPRD 19413330, 19651622, 20068231
S125 Phosphorylation HPRD 19413330, 19651622, 20068231
S128 Phosphorylation HPRD 19651622
S131 Phosphorylation HPRD 19413330, 20068231
S303 Phosphorylation HPRD 18669648
S312 Phosphorylation HPRD 18669648
T314 Phosphorylation HPRD 18669648
S362 Phosphorylation HPRD 20068231
S364 Phosphorylation HPRD 18669648, 20068231
T366 Phosphorylation HPRD 19413330
T367 Phosphorylation HPRD 18669648
T369 Phosphorylation HPRD 19413330
S370 Phosphorylation HPRD 19413330, 18669648, 20068231
T461 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K229 Q229 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K229 E229 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K256 T256 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ icgc ]
K318 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S324 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S362 I362 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S406 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S410 I410 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S412 L412 Biomuta DOID:1319 / brain cancer [ cosmic ]
T421 A421 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S422 I422 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]