iPTMnet Report for Q15714 (TSC22D1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15714 / T22D1_HUMAN
Protein Name TSC22 domain family protein 1
Gene Name Name: TSC22D1
Synonyms:KIAA1994,TGFB1I4,TSC22;ORFNames:hucep-2;
Organism Homo sapiens (Human)

PRO ID PR:Q15714
DAG View
PRO Name TSC22 domain family protein 1 (human)
Definition A TSC22 domain family protein 1 that is encoded in the genome of human.
Short Label hTSC22D1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15714 (TSC22D1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S256 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus   UniProt 19690332
S288 Phosphorylation PhosphoSitePlus
T291 Phosphorylation PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
T439 O-Glycosylation GlyGen 29351928, 28657654, 35254053
T459 O-Glycosylation GlyGen 29351928, 28657654, 35254053
S823 O-Glycosylation GlyGen 29351928, 28657654, 35254053
S936 Phosphorylation PhosphoSitePlus
K992 Ubiquitination PhosphoSitePlus
Y997 Phosphorylation PhosphoSitePlus
K1007 Ubiquitination PhosphoSitePlus
K1011 Ubiquitination PhosphoSitePlus
K1016 Ubiquitination PhosphoSitePlus
S1018 Phosphorylation PhosphoSitePlus
K1028 Ubiquitination PhosphoSitePlus
S1066 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S42 Phosphorylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
S64 Phosphorylation HPRD 20068231
Y68 Phosphorylation HPRD   PhosphoSitePlus 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S42 N42 Biomuta DOID:1612 / breast cancer [ cosmic ]
S263 T263 Biomuta DOID:263 / kidney cancer [ cosmic ]
S263 C263 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1018 F1018 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1066 L1066 Biomuta DOID:5041 / esophageal cancer [ cosmic ]