iPTMnet Report for Q15699 (ALX1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15699 / ALX1_HUMAN
Protein Name ALX homeobox protein 1
Gene Name Name: ALX1
Synonyms:CART1;
Organism Homo sapiens (Human)

PRO ID PR:Q15699
DAG View
PRO Name ALX homeobox protein 1 (human)
Definition An ALX homeobox protein 1 that is encoded in the genome of human.
Short Label hALX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15699 (ALX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 23186163
S45 Phosphorylation HPRD   PhosphoSitePlus 20068231
K48 Sumoylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus   UniProt 23186163
S105 Phosphorylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
Y156 Phosphorylation PhosphoSitePlus
T169 Phosphorylation PhosphoSitePlus
T172 Phosphorylation PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus   UniProt 23186163
S307 Phosphorylation PhosphoSitePlus
R312 Methylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S128 F128 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S128 C128 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R312 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
R312 Q312 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S323 L323 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]