iPTMnet Report for Q15672 (TWIST1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15672 / TWST1_HUMAN
Protein Name Twist-related protein 1
Gene Name Name: TWIST1
Synonyms:BHLHA38,TWIST;
Organism Homo sapiens (Human)

PRO ID PR:Q15672
DAG View
PRO Name twist-related protein 1 (human)
Definition A twist-related protein 1 that is encoded in the genome of human.
Short Label hTWIST1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15672 (TWIST1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation P28482 (MAPK1) neXtProt 21502402
S18 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 21559372
S20 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 21559372
K33 Methylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
S42 Phosphorylation P31749 (AKT1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 28915063, 20400976
S45 Phosphorylation PhosphoSitePlus
S68 Phosphorylation P27361 (MAPK3) , Q15759 (MAPK11) , P45983 (MAPK8) , Q16539 (MAPK14) , P28482 (MAPK1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 21502402, 26959880, 26975371, ...32679125
K73 Acetylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K76 Acetylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
Y103 Phosphorylation PhosphoSitePlus   RLIMS-P 25893917
T121 Phosphorylation PhosphoSitePlus
S123 Phosphorylation P31749 (AKT1) neXtProt   PhosphoSitePlus 20400976
K133 Ubiquitination PhosphoSitePlus
T137 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K142 T142 Biomuta DOID:363 / uterine cancer [ icgc ]
K150 N150 Biomuta DOID:9256 / colorectal cancer [ cosmic ]