iPTMnet Report for Q15661 (TPSAB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15661 / TRYB1_HUMAN
Protein Name Tryptase alpha/beta-1 precursor
Gene Name Name: TPSAB1
Synonyms:TPS1,TPS2,TPSB1;
Organism Homo sapiens (Human)

PRO ID PR:Q15661
DAG View
PRO Name tryptase alpha/beta-1 (human)
Definition A tryptase alpha/beta-1 that is encoded in the genome of human.
Short Label hTPSAB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15661 (TPSAB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y97 Phosphorylation PhosphoSitePlus
N132 N-Glycosylation GlyGen 29741879
C188 S-Nitrosylation dbSNO 25040305
Y197 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
N233 N-Glycosylation GlyGen   UniProt 29741879, 19159218


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N132 K132 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ]