Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15642 / CIP4_HUMAN
Protein Name Cdc42-interacting protein 4
Gene Name Name: TRIP10
Synonyms:CIP4,STOT,STP;
Organism Homo sapiens (Human)

PRO ID PR:Q15642
DAG View
PRO Name Cdc42-interacting protein 4 (human)
Definition A Cdc42-interacting protein 4 that is encoded in the genome of human.
Short Label hTRIP10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15642 (TRIP10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R27 Methylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K104 Acetylation PhosphoSitePlus
K132 Acetylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
Y190 Phosphorylation PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
T225 Phosphorylation RLIMS-P 31319138
S235 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
S296 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 24275569, 18088087, 20068231
S298 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S299 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 18669648, 23186163, ...17081983
T302 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S304 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S335 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S343 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S351 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S363 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
S477 Phosphorylation PhosphoSitePlus
S482 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 20068231
T579 Phosphorylation PhosphoSitePlus
Y590 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S296 Phosphorylation HPRD 17322306, 18088087, 18767875, ...19664994, 19651622, 18669648, 18707149, 19415658, 20068231
S298 Phosphorylation HPRD 17322306, 19651622, 18669648, ...19415658, 20068231
S299 Phosphorylation HPRD 18088087, 17081983, 19651622, ...18669648, 19415658, 20068231
T302 Phosphorylation HPRD 18669648, 20068231
S304 Phosphorylation HPRD 19651622, 18669648, 20068231
S426 Phosphorylation HPRD 17081983, 20068231
S428 Phosphorylation HPRD 17081983, 20068231
Y471 Phosphorylation HPRD 12456510
Site PTM Type PTM Enzyme Score Source PMID
Y471 Phosphorylation P12931 (SRC) PhosphoSitePlus 21525036
T544 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q15642 (TRIP10) T225 P60953 (CDC42) unknown eFIP 31319138


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S235 L235 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S288 I288 Biomuta DOID:3571 / liver cancer [ icgc ]