iPTMnet Report for Q15633 (TARBP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15633 / TRBP2_HUMAN
Protein Name RISC-loading complex subunit TARBP2
Gene Name Name: TARBP2
Synonyms:TRBP;
Organism Homo sapiens (Human)

PRO ID PR:Q15633
DAG View
PRO Name RISC-loading complex subunit TARBP2 (human)
Definition A RISC-loading complex subunit TARBP2 that is encoded in the genome of human.
Short Label hTARBP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15633 (TARBP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T30 Phosphorylation PhosphoSitePlus
K52 Sumoylation PhosphoSitePlus
T71 Phosphorylation PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus   RLIMS-P 26582366, 29540527
S152 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 26582366, 29540527, 24275569
S156 Phosphorylation PhosphoSitePlus
Y178 Phosphorylation PhosphoSitePlus
T179 Phosphorylation PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus   RLIMS-P 26582366, 29540527
S286 Phosphorylation PhosphoSitePlus   RLIMS-P 26582366, 29540527
K360 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S152 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S131 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S131 F131 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S152 F152 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T179 I179 Biomuta DOID:1324 / lung cancer [ cosmic ]
S184 T184 Biomuta DOID:4159 / skin cancer [ cosmic ]
S286 C286 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]