iPTMnet Report for Q15629 (TRAM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15629 / TRAM1_HUMAN
Protein Name Translocating chain-associated membrane protein 1
Gene Name Name: TRAM1
Synonyms:TRAM;
Organism Homo sapiens (Human)

PRO ID PR:Q15629
DAG View
PRO Name translocating chain-associated membrane protein 1 (human)
Definition A translocation-associated membrane protein 1 that is encoded in the genome of human.
Short Label hTRAM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15629 (TRAM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
C29 Methylation IEDB 31844290
K113 Ubiquitination PhosphoSitePlus
T162 Phosphorylation PhosphoSitePlus
Y246 Phosphorylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
C305 Methylation IEDB 31844290
S327 Phosphorylation PhosphoSitePlus
T339 Phosphorylation PhosphoSitePlus
T341 Phosphorylation PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
T350 Phosphorylation PhosphoSitePlus
N355 N-Glycosylation GlyGen 29741879
S365 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...16565220, 18669648, 19690332, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S365 Phosphorylation HPRD 19413330, 18691976, 16565220, ...19651622, 18669648, 18452278, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T162 I162 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic, icgc ]
S251 F251 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ]
T339 A339 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
N355 S355 Biomuta DOID:3571 / liver cancer [ cosmic ]
S365 F365 Biomuta [ cosmic ]