iPTMnet Report for Q15582 (TGFBI)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15582 / BGH3_HUMAN
Protein Name Transforming growth factor-beta-induced protein ig-h3 precursor
Gene Name Name: TGFBI
Synonyms:BIGH3;
Organism Homo sapiens (Human)

PRO ID PR:Q15582
DAG View
PRO Name transforming growth factor-beta-induced protein ig-h3 (human)
Definition A transforming growth factor-beta-induced protein ig-h3 that is encoded in the genome of human.
Short Label hTGFBI
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15582 (TGFBI) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S28 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S28 Phosphorylation PhosphoSitePlus
Y30 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus   UniProt 24275569
T457 Phosphorylation PhosphoSitePlus
Y537 Phosphorylation PhosphoSitePlus
K590 Ubiquitination PhosphoSitePlus
S591 Phosphorylation PhosphoSitePlus
S649 Phosphorylation PhosphoSitePlus
S667 Phosphorylation PhosphoSitePlus
Y674 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S37 G37 Biomuta DOID:3571 / liver cancer [ cosmic ]
K590 T590 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S649 F649 Biomuta DOID:4159 / skin cancer [ cosmic ]