iPTMnet Report for Q15561 (TEAD4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15561 / TEAD4_HUMAN
Protein Name Transcriptional enhancer factor TEF-3
Gene Name Name: TEAD4
Synonyms:RTEF1,TCF13L1,TEF3;
Organism Homo sapiens (Human)

PRO ID PR:Q15561
DAG View
PRO Name transcriptional enhancer factor TEF-3 (human)
Definition A transcriptional enhancer factor TEF-3 that is encoded in the genome of human.
Short Label hTEAD4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15561 (TEAD4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K65 Ubiquitination PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
Y84 Phosphorylation PhosphoSitePlus
K91 Methylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K123 Acetylation PhosphoSitePlus
K178 Sumoylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
Y271 Phosphorylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
K278 Acetylation PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
K282 Acetylation PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
Y349 Phosphorylation PhosphoSitePlus
Y352 Phosphorylation PhosphoSitePlus
Y357 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K73 N73 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K96 M96 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K278 R278 Biomuta DOID:184 / bone cancer [ cosmic ]
K282 M282 Biomuta DOID:3571 / liver cancer [ cosmic ]