Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15528 / MED22_HUMAN
Protein Name Mediator of RNA polymerase II transcription subunit 22
Gene Name Name: MED22
Synonyms:SURF5;
Organism Homo sapiens (Human)

PRO ID PR:Q15528
DAG View
PRO Name mediator of RNA polymerase II transcription subunit 22 (human)
Definition A mediator of RNA polymerase II transcription subunit 22 that is encoded in the genome of human.
Short Label hMED22
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15528 (MED22) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K11 Ubiquitination PhosphoSitePlus
K20 Ubiquitination PhosphoSitePlus
T34 Phosphorylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
Y59 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
T107 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T107 Phosphorylation HPRD 19664994
Site PTM Type PTM Enzyme Score Source PMID
T107 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K38 N38 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]