Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15468 / STIL_HUMAN
Protein Name SCL-interrupting locus protein
Gene Name Name: STIL
Synonyms:SIL;
Organism Homo sapiens (Human)

PRO ID PR:Q15468
DAG View
PRO Name SCL-interrupting locus protein (human)
Definition An SCL-interrupting locus protein that is encoded in the genome of human.
Short Label hSTIL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15468 (STIL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K54 Ubiquitination PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
T96 Phosphorylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
T336 Phosphorylation PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23186163, 29445034
S403 Phosphorylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
K416 Ubiquitination PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus
Y470 Phosphorylation PhosphoSitePlus
S475 Phosphorylation PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
K512 Acetylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
T591 Phosphorylation PhosphoSitePlus
S719 Phosphorylation PhosphoSitePlus
S753 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K755 Ubiquitination PhosphoSitePlus
S779 Phosphorylation PhosphoSitePlus   UniProt 23186163
S852 Phosphorylation PhosphoSitePlus
S869 Phosphorylation PhosphoSitePlus
S871 Phosphorylation RLIMS-P 25701666
S873 Phosphorylation RLIMS-P 25701666
S874 Phosphorylation RLIMS-P 25701666
K936 Ubiquitination PhosphoSitePlus
Y938 Phosphorylation PhosphoSitePlus
K954 Ubiquitination PhosphoSitePlus
K962 Ubiquitination PhosphoSitePlus
K991 Ubiquitination PhosphoSitePlus
K1000 Ubiquitination PhosphoSitePlus
S1004 Phosphorylation PhosphoSitePlus
K1008 Ubiquitination PhosphoSitePlus
S1011 Phosphorylation PhosphoSitePlus
K1014 Ubiquitination PhosphoSitePlus
S1061 Phosphorylation RLIMS-P 25342035
S1108 Phosphorylation P53350 (PLK1) PhosphoSitePlus   RLIMS-P 26101219, 31672968
S1111 Phosphorylation PhosphoSitePlus
S1116 Phosphorylation P53350 (PLK1) PhosphoSitePlus   RLIMS-P 25342035, 25701666, 26101219
T1119 Phosphorylation PhosphoSitePlus   RLIMS-P 25342035
K1120 Ubiquitination PhosphoSitePlus
S1132 Phosphorylation PhosphoSitePlus
S1135 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
K1168 Ubiquitination PhosphoSitePlus
K1206 Ubiquitination PhosphoSitePlus
K1214 Ubiquitination PhosphoSitePlus
K1223 Ubiquitination PhosphoSitePlus
S1225 Phosphorylation PhosphoSitePlus
K1234 Ubiquitination PhosphoSitePlus
K1243 Ubiquitination PhosphoSitePlus
T1250 Phosphorylation RLIMS-P 25701666
Site PTM Type PTM Enzyme Score Source PMID
S753 Phosphorylation HPRD 18669648
S1004 Phosphorylation HPRD 17924679
Site PTM Type PTM Enzyme Score Source PMID
S753 Phosphorylation HPRD 18669648
S1005 Phosphorylation HPRD 17924679


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q15468 (STIL) S1116 Q6UVJ0 (SASS6) increased_association eFIP 26101219


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K151 N151 Biomuta DOID:363 / uterine cancer [ tcga ]
S272 I272 Biomuta DOID:1793 / pancreatic cancer [ tcga ] DOID:363 / uterine cancer [ tcga ]
K372 N372 Biomuta DOID:363 / uterine cancer [ tcga ]
S375 P375 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S395 C395 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
K416 E416 Biomuta DOID:3571 / liver cancer [ tcga ]
S521 N521 Biomuta DOID:363 / uterine cancer [ icgc, tcga ]
S719 P719 Biomuta DOID:363 / uterine cancer [ tcga ]
S852 I852 Biomuta DOID:363 / uterine cancer [ tcga ]
S874 C874 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
K936 N936 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S1004 R1004 Biomuta DOID:3571 / liver cancer [ icgc ]
T1119 I1119 Biomuta DOID:1909 / melanoma [ icgc, tcga ]