iPTMnet Report for Q15465 (SHH)
Protein Information
UniProt AC / UniProt ID | Q15465 / SHH_HUMAN |
Protein Name | Sonic hedgehog protein precursor |
Gene Name | Name: SHH |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q15465 |
PRO Name | sonic hedgehog protein (human) |
Definition | A sonic hedgehog protein that is encoded in the genome of human. |
Short Label | hSHH |
Category | organism-gene |
Q15465 (SHH) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K32 | Acetylation | score1 | PhosphoSitePlus | |||
K37 | Acetylation | score1 | PhosphoSitePlus | |||
Y253 | Phosphorylation | score1 | PhosphoSitePlus | |||
N278 | N-Glycosylation | score2 | GlyGen UniProt | 16335952 | ||
Y316 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K32 | N32 | Biomuta | DOID:1612 / breast cancer [ cosmic ] |