Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15435 / PP1R7_HUMAN
Protein Name Protein phosphatase 1 regulatory subunit 7
Gene Name Name: PPP1R7
Synonyms:SDS22;
Organism Homo sapiens (Human)

PRO ID PR:Q15435
DAG View
PRO Name protein phosphatase 1 regulatory subunit 7 (human)
Definition A protein phosphatase 1 regulatory subunit 7 that is encoded in the genome of human.
Short Label hPPP1R7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15435 (PPP1R7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
S12 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S24 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 20068231, ...18318008
S27 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18318008, ...24275569, 20068231
K34 Acetylation PhosphoSitePlus
S36 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus   UniProt 20068231, 24275569
S47 Phosphorylation PhosphoSitePlus   UniProt 20068231, 24275569
K49 Ubiquitination PhosphoSitePlus
R54 Methylation PhosphoSitePlus
R76 Methylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
T243 Phosphorylation PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
T277 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y327 Phosphorylation PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation HPRD 18077418, 20068231, 18452278
S24 Phosphorylation HPRD 19413330, 19651622, 20068231
S27 Phosphorylation HPRD 19413330, 19651622, 20068231
S37 Phosphorylation HPRD 19651622, 20068231
S44 Phosphorylation HPRD 19651622, 20068231
S47 Phosphorylation HPRD 19651622, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S47 I47 Biomuta DOID:3571 / liver cancer [ icgc ]
R54 Q54 Biomuta DOID:9256 / colorectal cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]
R54 L54 Biomuta DOID:1324 / lung cancer [ tcga ]
K162 R162 Biomuta DOID:263 / kidney cancer [ cosmic, tcga ]
K222 N222 Biomuta DOID:1324 / lung cancer [ cosmic ]