iPTMnet Report for Q15431 (SYCP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15431 / SYCP1_HUMAN
Protein Name Synaptonemal complex protein 1
Gene Name Name: SYCP1
Synonyms:SCP1;
Organism Homo sapiens (Human)

PRO ID PR:Q15431
DAG View
PRO Name synaptonemal complex protein 1 (human)
Definition A synaptonemal complex protein 1 that is encoded in the genome of human.
Short Label hSYCP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15431 (SYCP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y110 Phosphorylation PhosphoSitePlus
K111 Acetylation PhosphoSitePlus
S122 O-Glycosylation GlyGen 30379171
T123 O-Glycosylation GlyGen 30379171
K157 Acetylation PhosphoSitePlus
K161 Acetylation PhosphoSitePlus
K170 Acetylation PhosphoSitePlus
Y211 Phosphorylation PhosphoSitePlus
Y257 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107
K295 Ubiquitination PhosphoSitePlus
Y664 Phosphorylation PhosphoSitePlus
Y721 Phosphorylation PhosphoSitePlus
T785 Phosphorylation PhosphoSitePlus
K789 Ubiquitination PhosphoSitePlus
K791 Ubiquitination PhosphoSitePlus
T819 Phosphorylation PhosphoSitePlus
Y838 Phosphorylation PhosphoSitePlus
T846 Phosphorylation PhosphoSitePlus
Y855 Phosphorylation PhosphoSitePlus
S892 Phosphorylation PhosphoSitePlus
K927 Acetylation PhosphoSitePlus
S934 Phosphorylation PhosphoSitePlus
T937 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y110 C110 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y257 F257 Biomuta DOID:1324 / lung cancer [ cosmic ]
K791 R791 Biomuta DOID:1324 / lung cancer [ cosmic ]
T846 A846 Biomuta DOID:1324 / lung cancer [ cosmic ]
T846 N846 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S892 L892 Biomuta DOID:4159 / skin cancer [ cosmic ]
S934 L934 Biomuta [ cosmic ]
T937 A937 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]