iPTMnet Report for Q15417 (CNN3)
Protein Information
UniProt AC / UniProt ID | Q15417 / CNN3_HUMAN |
Protein Name | Calponin-3 |
Gene Name | Name: CNN3 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q15417 |
PRO Name | calponin-3 (human) |
Definition | A calponin-3 that is encoded in the genome of human. |
Short Label | hCNN3 |
Category | organism-gene |
Q15417 (CNN3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T2 | Phosphorylation | score1 | PhosphoSitePlus | |||
K6 | Acetylation | score1 | PhosphoSitePlus | |||
K6 | Ubiquitination | score1 | PhosphoSitePlus | |||
S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y10 | Phosphorylation | score1 | PhosphoSitePlus | 18698806 | ||
Y10 | Phosphorylation | P12931 (SRC) | score1 | PhosphoSitePlus | 18698806 | |
S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
K23 | Acetylation | score1 | PhosphoSitePlus | |||
K23 | Ubiquitination | score1 | PhosphoSitePlus | |||
S43 | Phosphorylation | score1 | PhosphoSitePlus | |||
C59 | Methylation | score1 | IEDB | 31844290 | ||
C59 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
K156 | Acetylation | score1 | PhosphoSitePlus | |||
K158 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
S162 | Phosphorylation | score1 | PhosphoSitePlus | |||
K172 | Methylation | score1 | PhosphoSitePlus | |||
K172 | Ubiquitination | score1 | PhosphoSitePlus | |||
C173 | Methylation | score1 | IEDB | 31844290 | ||
C173 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
S175 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y182 | Phosphorylation | score1 | PhosphoSitePlus | |||
T184 | Phosphorylation | score1 | PhosphoSitePlus | |||
R185 | Methylation | score1 | PhosphoSitePlus | |||
K197 | Ubiquitination | score1 | PhosphoSitePlus | |||
S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
K212 | Ubiquitination | score1 | PhosphoSitePlus | |||
S215 | Phosphorylation | score1 | PhosphoSitePlus | |||
T224 | Phosphorylation | score1 | PhosphoSitePlus | |||
K232 | Ubiquitination | score1 | PhosphoSitePlus | |||
T234 | Phosphorylation | score1 | PhosphoSitePlus | |||
N240 | N-Glycosylation | score1 | GlyGen | 29741879, 24190977 | ||
T242 | Phosphorylation | score1 | PhosphoSitePlus | |||
S244 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17287340 | ||
K251 | Ubiquitination | score1 | PhosphoSitePlus | |||
S254 | Phosphorylation | score1 | PhosphoSitePlus | |||
K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
S259 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y261 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
C273 | Methylation | score1 | IEDB | 31844290 | ||
S285 | Phosphorylation | score1 | PhosphoSitePlus | |||
T288 | Phosphorylation | score1 | PhosphoSitePlus | |||
S293 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 20861310 | ||
S293 | Phosphorylation | O75116 (ROCK2) | score2 | PhosphoSitePlus | 20861310 | |
S296 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 20861310 | ||
Y300 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y308 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y316 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y320 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y322 | Phosphorylation | score1 | PhosphoSitePlus | |||
S323 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 17081983 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S162 | Phosphorylation | score0 | HPRD | 18212344 | ||
S244 | Phosphorylation | score0 | HPRD | 17287340 | ||
Y261 | Phosphorylation | score1 | HPRD | 15206927 | ||
Y261 | Phosphorylation | P06241 (FYN) | score1 | HPRD | 15206927 | |
T290 | Phosphorylation | score0 | HPRD | 17081983 | ||
S296 | Phosphorylation | score0 | HPRD | 17081983 | ||
S323 | Phosphorylation | score0 | HPRD | 17081983, 19664995 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S43 | N43 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
C173 | Y173 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
R185 | K185 | Biomuta | [ cosmic ] | |
S215 | I215 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
T224 | A224 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S244 | F244 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
T288 | K288 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
Y316 | H316 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
S323 | R323 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] |