Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15392 / DHC24_HUMAN
Protein Name Delta(24)-sterol reductase precursor
Gene Name Name: DHCR24
Synonyms:KIAA0018;
Organism Homo sapiens (Human)

PRO ID PR:Q15392
DAG View
PRO Name Delta(24)-sterol reductase (human)
Definition A Delta(24)-sterol reductase that is encoded in the genome of human.
Short Label hDHCR24
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15392 (DHCR24) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K76 Ubiquitination PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
T110 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
Y180 Phosphorylation PhosphoSitePlus
T188 Phosphorylation PhosphoSitePlus
Y190 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
Y299 Phosphorylation PhosphoSitePlus
Y300 Phosphorylation PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
K313 Methylation PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
Y321 Phosphorylation PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
T373 Phosphorylation PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
K427 Ubiquitination PhosphoSitePlus
K446 Sumoylation PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
K459 Ubiquitination PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
Y507 Phosphorylation PhosphoSitePlus
K509 Ubiquitination PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T110 Phosphorylation HPRD 17287340


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K87 T87 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
Y321 * Biomuta DOID:3571 / liver cancer [ icgc ]
Y507 * Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]