iPTMnet Report for Q15390 (MTFR1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15390 / MTFR1_HUMAN
Protein Name Mitochondrial fission regulator 1 precursor
Gene Name Name: MTFR1
Synonyms:CHPPR,FAM54A2,KIAA0009;
Organism Homo sapiens (Human)

PRO ID PR:Q15390
DAG View
PRO Name mitochondrial fission regulator 1 (human)
Definition A mitochondrial fission regulator 1 that is encoded in the genome of human.
Short Label hMTFR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15390 (MTFR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus
Y30 Phosphorylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
S119 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...24275569
S124 Phosphorylation PhosphoSitePlus
T132 Phosphorylation PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
K217 Acetylation PhosphoSitePlus
K223 Acetylation PhosphoSitePlus
K227 Acetylation PhosphoSitePlus
Y286 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
S290 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S301 O-Glycosylation GlyGen 30620550
Site PTM Type PTM Enzyme Score Source PMID
Y30 Phosphorylation HPRD 17924679
S32 Phosphorylation HPRD 17924679, 18452278
S33 Phosphorylation HPRD 17924679, 18452278
S119 Phosphorylation HPRD 19651622, 18669648, 20068231
S290 Phosphorylation HPRD 17525332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S19 N19 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S22 L22 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S32 L32 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
S119 F119 Biomuta DOID:4159 / skin cancer [ cosmic ]
S290 I290 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]