Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15334 / L2GL1_HUMAN
Protein Name Lethal(2) giant larvae protein homolog 1
Gene Name Name: LLGL1
Synonyms:DLG4,HUGL,HUGL1;
Organism Homo sapiens (Human)

PRO ID PR:Q15334
DAG View
PRO Name lethal(2) giant larvae protein homolog 1 (human)
Definition A lethal(2) giant larvae protein homolog 1 that is encoded in the genome of human.
Short Label hLLGL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15334 (LLGL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K17 Ubiquitination PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
S123 O-Glycosylation GlyGen 23301498, 29351928
K293 Ubiquitination PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
K502 Ubiquitination PhosphoSitePlus
Y509 Phosphorylation PhosphoSitePlus
S510 Phosphorylation PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
T526 Phosphorylation PhosphoSitePlus
S553 Phosphorylation PhosphoSitePlus
T567 Phosphorylation PhosphoSitePlus
K569 Ubiquitination PhosphoSitePlus
S655 Phosphorylation PhosphoSitePlus
K657 Methylation PhosphoSitePlus
S659 Phosphorylation P41743 (PRKCI) neXtProt   PhosphoSitePlus 12725730
S663 Phosphorylation PhosphoSitePlus   UniProt 12725730
S670 Phosphorylation PhosphoSitePlus
K684 Ubiquitination PhosphoSitePlus
C697 S-Nitrosylation dbSNO 26338901
T704 Phosphorylation PhosphoSitePlus
K780 Ubiquitination PhosphoSitePlus
K840 Ubiquitination PhosphoSitePlus
K848 Ubiquitination PhosphoSitePlus
K906 Ubiquitination PhosphoSitePlus
S961 Phosphorylation PhosphoSitePlus
S967 Phosphorylation PhosphoSitePlus
S1040 Phosphorylation PhosphoSitePlus
S1044 Phosphorylation PhosphoSitePlus
K1046 Ubiquitination PhosphoSitePlus
C1059 S-Nitrosylation dbSNO 26338901


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S553 C553 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S553 G553 Biomuta DOID:1324 / lung cancer [ cosmic ]
S659 A659 Biomuta DOID:3571 / liver cancer [ icgc ]
K684 N684 Biomuta DOID:3571 / liver cancer [ icgc ]