iPTMnet Report for Q15334 (LLGL1)
Protein Information
UniProt AC / UniProt ID | Q15334 / L2GL1_HUMAN |
Protein Name | Lethal(2) giant larvae protein homolog 1 |
Gene Name | Name: LLGL1 Synonyms:DLG4,HUGL,HUGL1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q15334 |
PRO Name | lethal(2) giant larvae protein homolog 1 (human) |
Definition | A lethal(2) giant larvae protein homolog 1 that is encoded in the genome of human. |
Short Label | hLLGL1 |
Category | organism-gene |
Q15334 (LLGL1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K17 | Ubiquitination | score1 | PhosphoSitePlus | |||
K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
K27 | Ubiquitination | score1 | PhosphoSitePlus | |||
K59 | Ubiquitination | score1 | PhosphoSitePlus | |||
S123 | O-Glycosylation | score1 | GlyGen | 23301498, 30379171, 34725712, ... | ||
K293 | Ubiquitination | score1 | PhosphoSitePlus | |||
S488 | Phosphorylation | score1 | PhosphoSitePlus | |||
K502 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y509 | Phosphorylation | score1 | PhosphoSitePlus | |||
S510 | Phosphorylation | score1 | PhosphoSitePlus | |||
K519 | Ubiquitination | score1 | PhosphoSitePlus | |||
T526 | Phosphorylation | score1 | PhosphoSitePlus | |||
S553 | Phosphorylation | score1 | PhosphoSitePlus | |||
T567 | Phosphorylation | score1 | PhosphoSitePlus | |||
K569 | Ubiquitination | score1 | PhosphoSitePlus | |||
S655 | Phosphorylation | score1 | PhosphoSitePlus | |||
K657 | Methylation | score1 | PhosphoSitePlus | |||
S659 | Phosphorylation | P41743 (PRKCI) | score3 | neXtProt PhosphoSitePlus | 12725730 | |
S663 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 12725730 | ||
S670 | Phosphorylation | score1 | PhosphoSitePlus | |||
S673 | Phosphorylation | score1 | PhosphoSitePlus | |||
K684 | Ubiquitination | score1 | PhosphoSitePlus | |||
C697 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
T704 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 31848261 | ||
K780 | Ubiquitination | score1 | PhosphoSitePlus | |||
K840 | Ubiquitination | score1 | PhosphoSitePlus | |||
K848 | Ubiquitination | score1 | PhosphoSitePlus | |||
K906 | Ubiquitination | score1 | PhosphoSitePlus | |||
S961 | Phosphorylation | score1 | PhosphoSitePlus | |||
S967 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1040 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1044 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1046 | Ubiquitination | score1 | PhosphoSitePlus | |||
C1059 | S-Nitrosylation | score0 | dbSNO | 26338901 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T526 | A526 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S553 | C553 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S553 | G553 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S655 | F655 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S659 | A659 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
S961 | N961 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
C1059 | Y1059 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |