iPTMnet Report for Q15306 (IRF4)
Protein Information
UniProt AC / UniProt ID | Q15306 / IRF4_HUMAN |
Protein Name | Interferon regulatory factor 4 |
Gene Name | Name: IRF4 Synonyms:MUM1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q15306 |
PRO Name | interferon regulatory factor 4 (human) |
Definition | An interferon regulatory factor 4 that is encoded in the genome of human. |
Short Label | hIRF4 |
Category | organism-gene |
Q15306 (IRF4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C19 | Methylation | score1 | IEDB | 31844290 | ||
K36 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y37 | Phosphorylation | score1 | PhosphoSitePlus | |||
S48 | Phosphorylation | score1 | PhosphoSitePlus | |||
K59 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y62 | Phosphorylation | score1 | PhosphoSitePlus | |||
K103 | Acetylation | score1 | PhosphoSitePlus | |||
K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y122 | Phosphorylation | score1 | PhosphoSitePlus | |||
K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y125 | Phosphorylation | score1 | PhosphoSitePlus | |||
S177 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y181 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y192 | Phosphorylation | score1 | PhosphoSitePlus | |||
R201 | Methylation | score1 | PhosphoSitePlus | |||
C250 | Methylation | score1 | IEDB | 31844290 | ||
K264 | Ubiquitination | score1 | PhosphoSitePlus | |||
K306 | Ubiquitination | score1 | PhosphoSitePlus | |||
S309 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
Y325 | Phosphorylation | score1 | PhosphoSitePlus | |||
K327 | Ubiquitination | score1 | PhosphoSitePlus | |||
K349 | Ubiquitination | score1 | PhosphoSitePlus | |||
C356 | Methylation | score1 | IEDB | 31844290 | ||
K357 | Ubiquitination | score1 | PhosphoSitePlus | |||
K399 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y414 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y428 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y440 | Phosphorylation | score1 | PhosphoSitePlus | |||
S447 | Phosphorylation | O75116 (ROCK2) | score3 | PhosphoSitePlus Signor | 20697158 | |
S448 | Phosphorylation | O75116 (ROCK2) | score1 | Signor | 20697158 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C19 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K36 | N36 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
Y37 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S48 | R48 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K59 | R59 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
Y62 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K123 | R123 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
Y192 | H192 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
R201 | H201 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K264 | R264 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
K306 | N306 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
C356 | Y356 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y428 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y428 | H428 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S447 | Y447 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |