iPTMnet Report for Q15293 (RCN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15293 / RCN1_HUMAN
Protein Name Reticulocalbin-1 precursor
Gene Name Name: RCN1
Synonyms:RCN;
Organism Homo sapiens (Human)

PRO ID PR:Q15293
DAG View
PRO Name reticulocalbin-1 (human)
Definition A reticulocalbin-1 that is encoded in the genome of human.
Short Label hRCN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15293 (RCN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S43 O-Glycosylation GlyGen 34846842
N53 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
S55 O-Glycosylation GlyGen 34846842, 35138101, 34725712, ...30059200, 35254053, 34019948, 32119511, 35289036, 22121020, 22661428
S55 Phosphorylation PhosphoSitePlus   UniProt 24275569
K70 Ubiquitination PhosphoSitePlus
T71 Phosphorylation PhosphoSitePlus
T76 Phosphorylation PhosphoSitePlus   UniProt 20068231, 24275569
S80 Phosphorylation PhosphoSitePlus   UniProt 26091039, 24275569
K81 Acetylation PhosphoSitePlus
K81 Methylation PhosphoSitePlus
K81 Sumoylation PhosphoSitePlus
R83 Methylation PhosphoSitePlus
K86 Acetylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
R90 Methylation PhosphoSitePlus
T100 Phosphorylation PhosphoSitePlus
T101 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
R114 Methylation PhosphoSitePlus
Y115 Phosphorylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus
Y147 Phosphorylation PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K166 Acetylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
T185 Phosphorylation PhosphoSitePlus
T192 O-Glycosylation GlyGen 25813380
T192 Phosphorylation PhosphoSitePlus
T211 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
R249 Methylation PhosphoSitePlus
R270 Methylation PhosphoSitePlus
Y278 Phosphorylation PhosphoSitePlus
R286 Methylation PhosphoSitePlus
Y290 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N53 N-Glycosylation PRO 29741879
T76 Phosphorylation HPRD 20068231
S80 Phosphorylation HPRD 20166139, 18702456


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S43 L43 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K70 N70 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]
R90 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
K134 T134 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K134 N134 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
Y145 C145 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S234 F234 Biomuta DOID:4159 / skin cancer [ cosmic ]
R249 Q249 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R270 C270 Biomuta [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
K294 T294 Biomuta DOID:9256 / colorectal cancer [ cosmic ]