iPTMnet Report for Q15291 (RBBP5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15291 / RBBP5_HUMAN
Protein Name Retinoblastoma-binding protein 5
Gene Name Name: RBBP5
Synonyms:RBQ3;
Organism Homo sapiens (Human)

PRO ID PR:Q15291
DAG View
PRO Name retinoblastoma-binding protein 5 (human)
Definition A retinoblastoma-binding protein 5 that is encoded in the genome of human.
Short Label hRBBP5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15291 (RBBP5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
Y13 Phosphorylation PhosphoSitePlus
T20 Phosphorylation PhosphoSitePlus
T55 Phosphorylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
R162 Methylation PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
S182 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
T193 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
T198 Phosphorylation PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
T252 Phosphorylation PhosphoSitePlus   UniProt 7558034
K256 Ubiquitination PhosphoSitePlus
K281 Acetylation PhosphoSitePlus
Y345 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus   UniProt 17081983
S388 Phosphorylation PhosphoSitePlus   UniProt 20068231
S389 Phosphorylation PhosphoSitePlus   UniProt 20068231
K397 Sumoylation PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus   UniProt 7558034
K500 Acetylation PhosphoSitePlus
R508 Methylation PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
K519 Acetylation PhosphoSitePlus
S525 Phosphorylation PhosphoSitePlus   UniProt 21406692
Site PTM Type PTM Enzyme Score Source PMID
S130 Phosphorylation HPRD 19664994, 20068231
S138 Phosphorylation HPRD 20068231
T180 Phosphorylation HPRD 20068231
S182 Phosphorylation HPRD 17525332, 20068231
S188 Phosphorylation HPRD 20068231
T193 Phosphorylation HPRD 17525332
S350 Phosphorylation HPRD 17081983, 18452278
S388 Phosphorylation HPRD 17081983, 20068231, 18452278
S389 Phosphorylation HPRD 17081983, 20068231, 18452278
S497 Phosphorylation HPRD 19651622, 17081983, 20068231
S525 Phosphorylation HPRD 18077418, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S490 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S130 C130 Biomuta DOID:1324 / lung cancer [ cosmic ]
S138 * Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
T193 S193 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S389 R389 Biomuta DOID:4159 / skin cancer [ cosmic ]
S497 C497 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]