Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15276 / RABE1_HUMAN
Protein Name Rab GTPase-binding effector protein 1
Gene Name Name: RABEP1
Synonyms:RAB5EP,RABPT5,RABPT5A;
Organism Homo sapiens (Human)

PRO ID PR:Q15276
DAG View
PRO Name Rab GTPase-binding effector protein 1 (human)
Definition A Rab GTPase-binding effector protein 1 that is encoded in the genome of human.
Short Label hRABEP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15276 (RABEP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
S8 Phosphorylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
T203 Phosphorylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
Y223 Phosphorylation PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
K282 Acetylation PhosphoSitePlus   UniProt 19608861
T306 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus   UniProt 24275569
S377 Phosphorylation PhosphoSitePlus   UniProt 23186163
K392 Ubiquitination PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
S407 Phosphorylation Q15139 (PRKD1) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 23186163, 16964243, ...18669648, 24275569, 22975325, 19690332, 20068231
T408 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18088087, 24275569
S410 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 24275569, 18088087, 20068231
T413 Phosphorylation PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
K420 Ubiquitination PhosphoSitePlus
K427 Ubiquitination PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
T480 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y501 Phosphorylation PhosphoSitePlus
S503 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S511 Phosphorylation PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
K528 Ubiquitination PhosphoSitePlus
T553 Phosphorylation PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
K586 Ubiquitination PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus
S651 Phosphorylation PhosphoSitePlus
K701 Ubiquitination PhosphoSitePlus
K745 Ubiquitination PhosphoSitePlus
K765 Ubiquitination PhosphoSitePlus
S766 Phosphorylation PhosphoSitePlus
S771 Phosphorylation PhosphoSitePlus
K784 Ubiquitination PhosphoSitePlus
T792 Phosphorylation PhosphoSitePlus
K852 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S407 Phosphorylation HPRD 19413330, 16964243, 18767875, ...19664994, 19651622, 18669648, 20068231, 17081983
T408 Phosphorylation HPRD 19413330, 19651622, 18669648, ...18088087, 17081983
S410 Phosphorylation HPRD 19413330, 17322306, 18088087, ...19651622, 18669648, 20068231
T413 Phosphorylation HPRD 19651622
S414 Phosphorylation HPRD 19651622
T480 Phosphorylation HPRD 18669648, 20068231
S503 Phosphorylation HPRD 18669648, 20068231
S766 Phosphorylation HPRD 18452278
S771 Phosphorylation HPRD 18452278
T792 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S407 Phosphorylation HPRD 19413330, 16964243, 18767875, ...19664994, 19651622, 18669648, 20068231, 17081983
T408 Phosphorylation HPRD 19413330, 19651622, 18669648, ...18088087, 17081983
S410 Phosphorylation HPRD 19413330, 17322306, 18088087, ...19651622, 18669648, 20068231
T413 Phosphorylation HPRD 19651622
S414 Phosphorylation HPRD 19651622
T480 Phosphorylation HPRD 18669648, 20068231
S503 Phosphorylation HPRD 18669648, 20068231
T759 Phosphorylation HPRD 20068231
K768 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K23 T23 Biomuta DOID:363 / uterine cancer [ tcga ]
K42 N42 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K107 I107 Biomuta DOID:363 / uterine cancer [ tcga ]
T203 I203 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S370 N370 Biomuta DOID:363 / uterine cancer [ tcga ]
S374 L374 Biomuta DOID:1612 / breast cancer [ cosmic ]
T480 I480 Biomuta DOID:10534 / stomach cancer [ tcga ]
K586 N586 Biomuta DOID:3571 / liver cancer [ icgc ]
K852 T852 Biomuta DOID:3571 / liver cancer [ icgc ]