iPTMnet Report for Q15256 (PTPRR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15256 / PTPRR_HUMAN
Protein Name Receptor-type tyrosine-protein phosphatase R precursor
Gene Name Name: PTPRR
Synonyms:ECPTP,PTPRQ;
Organism Homo sapiens (Human)

PRO ID PR:Q15256
DAG View
PRO Name receptor-type tyrosine-protein phosphatase R (human)
Definition A receptor-type tyrosine-protein phosphatase R that is encoded in the genome of human.
Short Label hPTPRR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15256 (PTPRR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 O-Glycosylation GlyGen   UniProt 25326458
Y44 Phosphorylation PhosphoSitePlus
Y62 Phosphorylation PhosphoSitePlus
S75 Phosphorylation IEDB 35494241
S272 Phosphorylation PhosphoSitePlus
T316 O-Glycosylation GlyGen 30379171, 28657654
S324 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
T361 Phosphorylation PhosphoSitePlus
Y370 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
S430 Phosphorylation PhosphoSitePlus
T440 Phosphorylation PhosphoSitePlus
S456 Phosphorylation PhosphoSitePlus
Y504 Phosphorylation PhosphoSitePlus
Y547 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S23 L23 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y44 H44 Biomuta DOID:4159 / skin cancer [ cosmic ]
S272 L272 Biomuta DOID:4159 / skin cancer [ cosmic ]
S342 F342 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T361 A361 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T361 I361 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y547 C547 Biomuta DOID:9256 / colorectal cancer [ cosmic ]