iPTMnet Report for Q15061 (WDR43)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15061 / WDR43_HUMAN
Protein Name WD repeat-containing protein 43
Gene Name Name: WDR43
Synonyms:KIAA0007,UTP5;
Organism Homo sapiens (Human)

PRO ID PR:Q15061
DAG View
PRO Name WD repeat-containing protein 43 (human)
Definition A WD repeat-containing protein 43 that is encoded in the genome of human.
Short Label hWDR43
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15061 (WDR43) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S77 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 20068231
S85 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K181 Methylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus
T189 Phosphorylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K198 Acetylation PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
K309 Sumoylation PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
T321 Phosphorylation PhosphoSitePlus   UniProt 23186163
K324 Ubiquitination PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
T358 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
K384 Sumoylation PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
T394 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S399 Phosphorylation PhosphoSitePlus   UniProt 20068231
K402 Ubiquitination PhosphoSitePlus
K416 Ubiquitination PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
S431 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...16565220, 18669648, 20068231
S437 Phosphorylation PhosphoSitePlus   UniProt 21406692
K454 Ubiquitination PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
T510 Phosphorylation PhosphoSitePlus
K511 Ubiquitination PhosphoSitePlus
K564 Ubiquitination PhosphoSitePlus
S590 Phosphorylation PhosphoSitePlus   UniProt 21406692
S603 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
S608 Phosphorylation PhosphoSitePlus
S628 Phosphorylation PhosphoSitePlus
S630 Phosphorylation PhosphoSitePlus
T656 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231
S658 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231
S666 Phosphorylation PhosphoSitePlus
S674 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S77 I77 Biomuta DOID:3571 / liver cancer [ icgc ]
K119 T119 Biomuta DOID:3070 / malignant glioma [ tcga ]
S185 L185 Biomuta DOID:1324 / lung cancer [ tcga ]
K309 T309 Biomuta DOID:363 / uterine cancer [ tcga ]
K331 E331 Biomuta DOID:363 / uterine cancer [ tcga ]
K384 N384 Biomuta DOID:2531 / hematologic cancer [ icgc ]
K391 E391 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K402 E402 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
K480 N480 Biomuta DOID:1324 / lung cancer [ cosmic ]
K511 N511 Biomuta DOID:1612 / breast cancer [ cosmic ]
S666 P666 Biomuta DOID:1612 / breast cancer [ icgc ]