iPTMnet Report for Q15050 (RRS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15050 / RRS1_HUMAN
Protein Name Ribosome biogenesis regulatory protein homolog
Gene Name Name: RRS1
Synonyms:KIAA0112,RRR;
Organism Homo sapiens (Human)

PRO ID PR:Q15050
DAG View
PRO Name ribosome biogenesis regulatory protein homolog (human)
Definition A ribosome biogenesis regulatory protein that is encoded in the genome of human.
Short Label hRRS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15050 (RRS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378, 22223895
S5 Phosphorylation PhosphoSitePlus   UniProt 23186163
T56 Phosphorylation PhosphoSitePlus
T96 O-Glycosylation GlyGen 23301498, 35083852, 33465208
Y146 Phosphorylation PhosphoSitePlus
T153 Phosphorylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
K184 Sumoylation PhosphoSitePlus
K215 Acetylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
K313 Acetylation PhosphoSitePlus
K322 Acetylation PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
K333 Acetylation PhosphoSitePlus
S344 Phosphorylation HPRD   PhosphoSitePlus 19007248
K352 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T56 S56 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T96 A96 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K173 N173 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S307 G307 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S344 Y344 Biomuta DOID:363 / uterine cancer [ icgc ]
S344 F344 Biomuta DOID:363 / uterine cancer [ icgc ]