iPTMnet Report for Q15042 (RAB3GAP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15042 / RB3GP_HUMAN
Protein Name Rab3 GTPase-activating protein catalytic subunit
Gene Name Name: RAB3GAP1
Synonyms:KIAA0066,RAB3GAP;
Organism Homo sapiens (Human)

PRO ID PR:Q15042
DAG View
PRO Name Rab3 GTPase-activating protein catalytic subunit (human)
Definition A Rab3 GTPase-activating protein catalytic subunit that is encoded in the genome of human.
Short Label hRAB3GAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15042 (RAB3GAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
C145 Methylation IEDB 31844290
T188 Phosphorylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
T341 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus   UniProt 23186163
T386 Phosphorylation PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
K475 Sumoylation PhosphoSitePlus
K527 Acetylation PhosphoSitePlus
K534 Acetylation PhosphoSitePlus
K535 Ubiquitination PhosphoSitePlus
T536 Phosphorylation PhosphoSitePlus
S537 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S539 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T542 Phosphorylation PhosphoSitePlus
K562 Ubiquitination PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus
S579 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S581 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S590 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 24275569
S664 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S676 Phosphorylation PhosphoSitePlus
K772 Ubiquitination PhosphoSitePlus
K805 Ubiquitination PhosphoSitePlus
K809 Ubiquitination PhosphoSitePlus
K817 Ubiquitination PhosphoSitePlus
K857 Ubiquitination PhosphoSitePlus
R887 Methylation PhosphoSitePlus
R892 Methylation PhosphoSitePlus
K896 Ubiquitination PhosphoSitePlus
T908 Phosphorylation PhosphoSitePlus   UniProt 23186163
K915 Ubiquitination PhosphoSitePlus
S919 Phosphorylation PhosphoSitePlus
S927 Phosphorylation PhosphoSitePlus
S929 Phosphorylation PhosphoSitePlus
K953 Ubiquitination PhosphoSitePlus
K965 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T536 Phosphorylation HPRD 20166139, 20068231
S537 Phosphorylation HPRD 19651622, 20166139, 18669648, ...20068231
S539 Phosphorylation HPRD 20166139, 18767875, 18669648
T542 Phosphorylation HPRD 20166139
S577 Phosphorylation HPRD 17081983
S579 Phosphorylation HPRD 17081983
S581 Phosphorylation HPRD 17081983
S590 Phosphorylation HPRD 17081983
S664 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S5 N5 Biomuta [ cosmic ]
S5 R5 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S5 G5 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S9 F9 Biomuta DOID:4159 / skin cancer [ cosmic ]
K46 R46 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K50 N50 Biomuta DOID:363 / uterine cancer [ icgc ]
K215 N215 Biomuta DOID:363 / uterine cancer [ icgc ]
K215 T215 Biomuta DOID:363 / uterine cancer [ icgc ]
K527 N527 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K534 T534 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K535 T535 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T536 S536 Biomuta DOID:3571 / liver cancer [ cosmic ]
K562 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S676 N676 Biomuta DOID:363 / uterine cancer [ icgc ]
K857 I857 Biomuta DOID:363 / uterine cancer [ cosmic ]
R892 S892 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S927 Y927 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]