Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15029 / U5S1_HUMAN
Protein Name 116 kDa U5 small nuclear ribonucleoprotein component
Gene Name Name: EFTUD2
Synonyms:KIAA0031,SNRP116;
Organism Homo sapiens (Human)

PRO ID PR:Q15029
DAG View
PRO Name 116 kDa U5 small nuclear ribonucleoprotein component (human)
Definition A 116 kDa U5 small nuclear ribonucleoprotein component that is encoded in the genome of human.
Short Label hEFTUD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15029 (EFTUD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 21406692, 22223895, ...20068231
T3 Phosphorylation PhosphoSitePlus
Y6 Phosphorylation PhosphoSitePlus
S19 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 20068231, 21406692, 17081983, ...24275569
T30 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
K64 Sumoylation PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
Y73 Phosphorylation PhosphoSitePlus
T79 Phosphorylation PhosphoSitePlus
T86 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 15302935, 24275569
T90 Phosphorylation PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
Y167 Phosphorylation PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
T184 Phosphorylation PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
Y336 Phosphorylation PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
Y348 Phosphorylation PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
T353 Phosphorylation PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
K409 Ubiquitination PhosphoSitePlus
S459 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
S498 Phosphorylation PhosphoSitePlus
K508 Ubiquitination PhosphoSitePlus
S533 Phosphorylation PhosphoSitePlus
K561 Ubiquitination PhosphoSitePlus
T562 Phosphorylation PhosphoSitePlus
T564 Phosphorylation PhosphoSitePlus
T566 Phosphorylation PhosphoSitePlus
R569 Methylation PhosphoSitePlus
K581 Acetylation PhosphoSitePlus
K581 Ubiquitination PhosphoSitePlus
S598 Phosphorylation PhosphoSitePlus
K602 Ubiquitination PhosphoSitePlus
K612 Ubiquitination PhosphoSitePlus
K646 Ubiquitination PhosphoSitePlus
S649 Phosphorylation PhosphoSitePlus
K673 Ubiquitination PhosphoSitePlus
K681 Ubiquitination PhosphoSitePlus
K684 Ubiquitination PhosphoSitePlus
K694 Ubiquitination PhosphoSitePlus
K713 Ubiquitination PhosphoSitePlus
K721 Ubiquitination PhosphoSitePlus
T740 Phosphorylation PhosphoSitePlus
T749 Phosphorylation PhosphoSitePlus
S752 Phosphorylation PhosphoSitePlus
K756 Ubiquitination PhosphoSitePlus
K763 Ubiquitination PhosphoSitePlus
K788 Ubiquitination PhosphoSitePlus
K790 Acetylation PhosphoSitePlus
K790 Ubiquitination PhosphoSitePlus
R803 Methylation PhosphoSitePlus
T811 Phosphorylation PhosphoSitePlus
R813 Methylation PhosphoSitePlus
T824 Phosphorylation PhosphoSitePlus
S866 Phosphorylation PhosphoSitePlus
T885 Phosphorylation PhosphoSitePlus
K936 Ubiquitination PhosphoSitePlus
K941 Ubiquitination PhosphoSitePlus
S944 Phosphorylation PhosphoSitePlus
S948 Phosphorylation PhosphoSitePlus
S950 Phosphorylation PhosphoSitePlus
K951 Ubiquitination PhosphoSitePlus
K963 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T3 Phosphorylation HPRD 17081983, 18452278
Y6 Phosphorylation HPRD 17081983, 18452278
Y12 Phosphorylation HPRD 17081983
S19 Phosphorylation HPRD 19413330, 17081983, 20058876, ...18452278, 19651622, 20068231
T30 Phosphorylation HPRD 19413330, 17081983, 20068231
T86 Phosphorylation HPRD 18077418, 15302935, 18452278
T353 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y6 C6 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
T168 A168 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K182 N182 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T353 A353 Biomuta DOID:1324 / lung cancer [ cosmic ]
K405 N405 Biomuta DOID:1612 / breast cancer [ cosmic ]
K756 M756 Biomuta DOID:9256 / colorectal cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]
R813 S813 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S948 I948 Biomuta DOID:1909 / melanoma [ cosmic ]