Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15025 / TNIP1_HUMAN
Protein Name TNFAIP3-interacting protein 1
Gene Name Name: TNIP1
Synonyms:KIAA0113,NAF1;
Organism Homo sapiens (Human)

PRO ID PR:Q15025
DAG View
PRO Name TNFAIP3-interacting protein 1 (human)
Definition A TNFAIP3-interacting protein 1 that is encoded in the genome of human.
Short Label hTNIP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15025 (TNIP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus   UniProt 24275569
S79 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
K257 Acetylation PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus   UniProt 24275569
K301 Ubiquitination PhosphoSitePlus
T336 Phosphorylation PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
T350 Phosphorylation PhosphoSitePlus
T385 Phosphorylation PhosphoSitePlus
K389 Ubiquitination PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
S403 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243, ...20068231
T431 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S434 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
T438 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S442 Phosphorylation PhosphoSitePlus   UniProt 20068231
K452 Ubiquitination PhosphoSitePlus
K463 Acetylation PhosphoSitePlus
K467 Acetylation PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
K509 Ubiquitination PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
Y552 Phosphorylation PhosphoSitePlus   UniProt 17632516
S568 Phosphorylation PhosphoSitePlus
R571 Methylation PhosphoSitePlus
Y596 Phosphorylation PhosphoSitePlus
R599 Methylation PhosphoSitePlus   UniProt 24129315
S627 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
S77 Phosphorylation HPRD 20068231
S99 Phosphorylation HPRD 19413330
S266 Phosphorylation HPRD 20068231
S403 Phosphorylation HPRD 18669648, 19664994, 16964243, ...20068231
T431 Phosphorylation HPRD 18669648, 20068231
S434 Phosphorylation HPRD 20068231
S435 Phosphorylation HPRD 20068231
T438 Phosphorylation HPRD 18669648, 20068231
S442 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S79 F79 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S206 Y206 Biomuta DOID:2994 / germ cell cancer [ tcga ]
T431 A431 Biomuta DOID:1909 / melanoma [ cosmic ]
S568 Y568 Biomuta DOID:3571 / liver cancer [ icgc ]
Y596 * Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
R599 H599 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:10283 / prostate cancer [ icgc ]
R599 S599 Biomuta DOID:3571 / liver cancer [ icgc ]